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Cannabis for Central Pain Syndrome

Central pain syndrome is a neurological condition caused by damage to or dysfunction of the central nervous system (CNS). Central pain syndrome affects the brain, brainstem and spinal cord, and can be caused by multiple sclerosis (MS), epilepsy, Parkinson’s disease (PD), tumors, or a brain or spinal cord disease or injury. Pain is typically constant, may be moderate to severe in intensity, and is often made worse by touch, movement, emotions, and temperature changes, usually cold temperatures.

There is some very good evidence that cannabis can help treat chronic muscle, bone or neuropathic (nerve) pain, and many of the conditions that can cause central pain syndrome can be treated by cannabis. Cannabis’s sedative, anti-inflammatory, mood- & sleep- improving, and antioxidative effects all make it a potentially suitable treatment for central pain syndrome.

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Research Overview

Animal Study

1

Clinical Meta-analysis

5

Clinical Trial

1

Double Blind Clinical Trial

8

Meta-analysis

8

Total studies

Central Pain Syndrome

23

Positive

19 studies

83%

Inconclusive

3 studies

13%

Negative

1 studies

4%

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